Senior Scientist, Upstream Processing

USA - Pennsylvania - King of Prussia
Full-time
Posted Nov 9, 2026

Skills

Compliance
Operations
Problem Solving
Procurement
Recruiting

Job description

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programs, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a remote or hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company-wide benefits and life at GSK on our webpage Life at GSK | GSK

Find out more about GSK and R&D: Our approach to R&D

Senior Scientist, Upstream Processing

Join us as a Senior Scientist, Upstream Processing and play a key role in advancing scientific research that makes a real difference. You will work closely with diverse teams to design, carry out, and analyze experiments. Your insights will help shape innovative solutions that align with our mission to unite science, technology, and talent to get ahead of disease together. We value curiosity, teamwork, and a hands-on approach to solving important challenges. This role offers meaningful growth and impact as you develop your career in a supportive environment.

We value curious, motivated scientists who take ownership, communicate clearly, and thrive in a collaborative environment. This role offers you a chance to grow your skills, make a meaningful impact, and contribute to GSK’s mission of uniting science, technology, and talent to get ahead of disease together.

This role is located in Upper Merion, PA and requires working on-site. Hybrid or remote work options are not available for this position.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following :

•Leads the manufacture of clinical supply of investigational biopharmaceutical molecules. Specifically: hands-on cGMP large scale cell culture for use in early phase clinical trials

•Leads or works on projects and assignments where independent action and a high degree of initiative and knowledge are required for execution or to provide recommendations

•Supports the technology transfer process through active participation in ensuring that new processes fit and execute consistently

•Troubleshoots problems in the execution of processing activities; proactively assesses options and impact and takes action to rectify or communicate to appropriate decision makers

•Identifies process improvement opportunities with impact on safety, compliance, and efficiency/cost

•Maintains and performs compliance checks for documentation in logs, media forms, batch records, and electronic systems in accordance with company policy and legal requirements

•Strives for Right First Time in the manufacture of investigational material through attention, focus, planning, and adherence to procedural and regulatory expectations

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

•BS, MS, or PhD in Chemical Engineering, Biology, Chemistry, or other engineering or scientific field.

•A minimum of 3 years of direct GMP manufacturing experience or upstream processing experience in a biotechnology manufacturing facility or Pilot Plant.

Preferred Qualifications:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

•Thorough knowledge of Good Manufacturing Practices (GMP) regulations.

•Demonstrates good interpersonal skills and communicates well both verbally and through written communications.

•Maintains a professional and productive relationship with area management and co-workers.

•Thorough knowledge of routine laboratory/plant equipment and demonstrates high level of technical expertise with working familiarity with several methods, techniques, laboratory procedures and processes.

•Possess in-depth knowledge of how to analyze and interpret experimental/process data.

Join us in making a difference in patients’ lives around the world. We value your unique perspective and invite all interested candidates to submit their application.

#LI-GSK

Skills

Data Integrity, Detail-Oriented, Digital Fluency, Emergency Response, Financial Acumen, GxP Regulations, Lean Management, Manufacturing Processes, Problem Solving, Production Management, Project Coordination, Quality Compliance, Regulatory Compliance, Risk Awareness, Site Operations

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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