Integrated Biosciences, Inc.

Scientist / Senior Scientist, Medicinal Chemistry

Redwood City, CA
Full-time
$120K to $170K
Posted Nov 14, 2026

Job description

About Integrated Bio

Integrated Bio (integratedbio.com) is a scientific discovery company translating multimodal biological datasets into novel therapeutics, using our drug design platform and AI models. We are risk-takers, and we bet heavily that the future of societal health lies at the intersection of biological discovery, drug design, and AI. Our growing, star-studded team includes accomplished industry veterans and scientists from top universities, including Harvard, Princeton, and UCSB. Our team has deployed large-scale scientific discovery systems, brought drug candidates to the clinic, and published in Nature, Science, and Cell. We have accomplished all of this with no egos, and we are growing fast.

About the Role

We are looking for a Scientist or Senior Scientist in Medicinal Chemistry to turn chemical ideas into molecules that advance our discovery programs. You will work at the bench and across disciplines, using synthesis, biological results, and computational predictions to decide what to make next and why.

The role spans hit evaluation, hit-to-lead work, and lead optimization. You will help resolve the tradeoffs between activity, selectivity, and properties that determine whether a compound can become a medicine. Appointment at Scientist or Senior Scientist will depend on your relevant experience.

You will

•Propose compounds that test clear scientific hypotheses, then plan and carry out their synthesis, purification, and characterization.

•Establish structure–activity relationships (SAR) and use successive rounds of design and testing to improve compound performance.

•Interpret assay results alongside physicochemical, ADME, and pharmacokinetic data to select the most informative next experiments.

•Solve synthetic problems and coordinate with external chemistry partners to deliver compounds of suitable quality on agreed timelines.

•Discuss results and recommendations with cross functional colleagues, contributing chemistry expertise to program decisions.

•Keep complete research records, present findings, and document inventions that support the company's intellectual property.

You're a good fit if you have

•A Ph.D. in organic chemistry, medicinal chemistry, or a relevant discipline.

•A strong record of practical synthetic chemistry, including planning multistep routes and resolving difficult reactions.

•Experience with compound isolation and analytical methods such as NMR, LC-MS, and HPLC.

•Knowledge of how molecular structure affects biological activity, solubility, permeability, and metabolic stability.

•Sound experimental judgment: you can distinguish a useful result from an uncertain one and propose an experiment that resolves the uncertainty.

•The communication and organizational skills to work productively in a small team with changing research priorities.

Bonus points for

•Contributions to small molecule discovery programs, particularly those starting from phenotypic screens.

•Work in aging biology.

•Experience connecting pharmacokinetic and pharmacodynamic findings to compound design.

•Use of computational chemistry, cheminformatics, or AI tools to support research decisions.

•Experience coordinating research with CROs and an interest in how scientific progress translates into a biotech business.

What we offer

•Impact: You will play a key role in the work that drives our mission to cure age-related diseases. As an early hire, you will help shape the direction of the company, and your efforts will directly advance therapies with the potential to transform healthcare.

•People: You will work alongside a team of top-tier scientists and engineers, and directly with our founders, Dr. Felix Wong and Prof. Max Wilson. Our alumni have co-authored high-impact scientific papers and gone on to highly successful career trajectories.

•Room to grow: You will take on increasing scientific responsibility as your expertise and our programs develop, in a working environment that values initiative, constructive discussion, and respect for personal time.

Location & logistics

This onsite role is located at Redwood LIFE in Redwood City, CA, a modern and stunning life sciences complex in the Bay Area. 

Visa sponsorship available where applicable. We'll work with you to make it happen.

Timing: search underway November 2026 to January 2027.

Compensation & benefits

Salary band: $120K to $170K depending on experience and level (Scientist to Senior Scientist), plus substantial equity and performance bonus, commensurate with experience and the cost of living in the San Francisco Bay Area.

Integrated Bio offers all its employees exceptional benefits, including full health insurance coverage for you and a dependent, 401(k) plans, free lunch, vacation and sick days, and other longevity-related benefits.

Integrated Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.